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By synthesizing ApoE or ApoB amino acid fragments that bind to the low-density lipoprotein receptor (LRP) and conjugating them with our designed iron-chelating peptide J-bs5YP, we successfully transported the peptide into the brains of AD mice

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109 Interestingly, guanabenz, a well-known antihypertensive drug, also showed liver protection in AIH mice, which resulted from the reduction of ERS by inhibiting the proteolysis of ATF6